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Description

This means that less GLUT4 is inserted into the cell membrane

Gister and Hansson, 2017)

However, it is often used off-label for skin lightening because it manages to suppress the levels of melanin that regulate skin pigmentation, which had been seen in some patients of the above conditions

PMID: 39741193 Cell Mol Immunol 2024 Oct;21(10):1131-1144

To avoid non-specific cytotoxicity, especially in human cells, we additionally required low toxicity in U2-OS human bone osteosarcoma cells that we and others use routinely for image analysis due to their flattened morphology (Supplementary Fig